Virginia Tech Launches the First Clinical Trial for Rehabilitating Infant Stroke Victims

Apr 3, 2019 | Infants, Pediatrics, Stroke, Virginia Tech

Infant Stroke

Virginia Tech has launched the nation’s first multicenter pediatric stroke recovery trial for researchers and clinicians from 12 sites across the United States. It seeks to evaluate an innovative therapeutic approach to support 8-montnh old to 24-month old infants. The study is funded by a five-year, $13.5 million grant from the National Institute of Neurological Disorders and Stroke of the National Institutes of Health.

The Phase III “I-ACQUIRE Trial” will examine the effectiveness of pediatric therapy to increase upper extremity skills, motor development, and cognition in 240 children nationwide who experienced strokes when they were under four weeks old. Tested at a three-hour and six hour daily dose with four weeks to determine whether the three-hour daily sessions are effective, the study includes a specialty lightweight cast for the child’s non-impaired arm and hand that compels infants to increase their efforts to use the side impaired by the stroke.  The trial has the potential to transform the lives of 3,000 newly diagnosed infants annually.

Lead Research/Investigator

Sharon Landesman Ramey, Fralin Biomedical Research Institute, VTC

Warren Lo, pediatric neurologist, Nationwide Children’s Hospital; clinical professor pediatrics & neurology. The Ohio State University College of Medicine


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