University of Chicago Preclinical Research Reveals Antibiotics May Help Slow Alzheimer’s Symptoms

May 26, 2019 | Alzheimer, Antibiotics

University of Chicago preclinical researchers, testing hypotheses on mice, suggest antibiotics may reduce Alzheimer’s disease symptoms by impacting the gut bacteria. The Chicago team sought out to demonstrate how the long-term use of antibiotics could reduce inflammation and impede the growth of amyloid plaques in male mice.

A specific feature of Alzheimer’s disease, amyloid plaques form when specific proteins within the neurons of the brain accumulate and combine. They cause havoc on brain cell function and could trigger Alzheimer’s symptoms.

The University of Chicago Study

The study evidenced long-term antibiotic use may reduce inflammation and impede the movement of amyloid plaques in male mice.

Lead Research/Investigator

Sangram S. Sisodia, director of the Center for Molecular Neurobiology


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