University of Buffalo Study Ties Common Heartburn Meds to Kidney Disease & Failure

Mar 19, 2019 | Kidney Disease, PPI, Proton Pump Inhibitor, Renal

Kidney Disease


University of Buffalo researchers studied 190,000 patients over a 15 year period and found acid reflux drugs increase risk of kidney disease by 20%.  Common medications prescribed to treat heartburn, acid reflux and ulcers were linked to increased risk for kidney failure and chronic kidney disease.  Specifically, proton pump inhibitors (PPI) (a group of drugs that reduce the production of stomach acid) increased the risk of chronic kidney disease by 20%, resulting in four times the risk of kidney failure.  Billions of PPIs are sold per year. The population with the greatest risk are those 65 and older.

Lead Research/Investigator

Terry Dunn, PharmD

Category: PPI, Kidney Failure, Renal, Proton Pump Inhibitor


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