Investigators from King’s College London, Evelina London Children’s Hospital and University of Exeter will be leading one of the largest ever clinical trials in children with epilepsy, which aims uncover which treatment approach works best for children and their families.

Titled “Changing Agendas on Sleep, Treatment and Learning in Childhood Epilepsy (CASTLE) trial is funded by the National Institute for Health Research (NHIR). It represents one of a few trials seeking to compare antiepileptic drugs against active monitoring with no medication.  Other institutions providing support include The University of Liverpool, Edge Hill and Oxford Brookes Universities.

Lead Research/Investigators

Professor Deb Pal, King’s College London

Professor Paul Gringas, Evelina London Children’s Hospital

Professor Chris Morris, University of Exeter  

Source: Exeter

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