Stanford Researchers Shrink Stroke Damage in Mice by Calming Immune Cells

Jul 2, 2019 | Mice Studies, Preclinical Research, Stroke Damage

Laboratory transgenic mouse on the researcher's hand

Stanford scientists actually shrink stroke damage in mice by calming immune cells outside the brain. Rather than trying to fix stroke-damaged nerve cells, Stanford scientists took aim at a set of first-responder immune cells that live outside the brain to the site of a strike. The approach worked.

The Background

Stanford University School of Medicine investigators have shown that suppressing the activity of a small set of immune cells in mice after they’ve had a stroke substantially reduces their brain damage, boosts their survival rate and improves their motor performance days later.

The findings suggest that selectively subduing these immune cells, which migrate from the brain after a stroke, could meaningfully treat the stroke even days after it takes place.

Follow the link below to the Standard University School of Medicine source for the full read.

Lead Research/Investigator

Katrin Andreasson, Professor of Neurology and Neurological Sciences


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