St. Jude Identifies Method to Reduce Risk of Brain Damage in Leukemia Survivors

Sep 26, 2018 | Brain Damage, Leukemia, Sepsis

MDLinx reports that children with acute lymphoblastic leukemia (ALL) are at an extremely high risk of sepsis compared to the general population. In the first-published study of its kind, St. Jude Children’s Research Hospital scientists have discovered a link between sepsis during cancer treatment and long-term neurocognitive dysfunction. Sepsis is a potentially life-threatening condition in which the body wages a massive immune response to a bacterial infection of the blood. The study revealed survivors with a history of sepsis performed worse than other participants on tests measuring multiple neurocognitive domains, including executive function and attention span.

Lead Research/Investigators

Josh Wolf, MBBS

Kevin Krull, PhD


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