Sheba Medical Center Study Confirms Link Between use of Estrogen Patches & Improved Schizophrenia Symptoms

Aug 6, 2019 | CNS, Schizophrenia

Sheba Medical Center Study Confirms Link Between use of Estrogen Patches & Improved Schizophrenia Symptoms

Israeli researchers have confirmed a suspected link between the appliance of estrogen patches and the lessening of symptoms found in women with Schizophrenia. Led by Professor Mark Weiser of Israel’s elite national hospital Sheba Medical Center, Tel HaShomer, the research can potentially help bring better treatment to schizophrenia patients.

The Sheba Medical Center issues a press release announcing the findings. They noted that schizophrenia research has long been challenging with many inconsistent findings and positive outcomes often difficult to replicate. However, Sheba Medical Center reports that this study offers an independent replication of the findings of Australia’s Dr. Jayshri Kulkarni: that there is a link between estrogen patches and the improved symptoms of schizophrenia in women.

The Study

Conducted in the Republic of Maldova and led by a team from Sheba Medical Center, investigators administered estrogen patches to pre-menopausal women with schizophrenia for eight weeks. They found overall improved symptoms, including a reduction in delusions and hallucinations as well as improved social ability and sense of initiative.

Sheba Medical Center

An elite national medical center in Israel, the hospital itself was established in 1948 as Israel’s first military hospital to treat casualties from Israel’s war of independence. It has come a long way. Today it operates over 120 departments and clinics. With 1,700 beds and over 1,400 physicians, it handles over a million patients a year including 250,000 annual emergency visits. It conducts over two million medical tests of all type each year making it at the forefront of medical and clinical research. It operates on an approximate budget of $320 million.


The Stanley Medical Research Institute (non-profit organization in Washington DC)

Lead Research/Investigator

Professor Mark Weiser 


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