Precera Bioscience, Inc. (Precera) announces the publication of Assessment of Patient Medication Adherence, Medical Record Accuracy, and Medication Blood Concentrations for Prescription and Over-the-Counter Medications in JAMA Open Network on November 2, 2018, representing the first comprehensive study of medication therapy assessing hundreds of prescription and over-the-counter medications simultaneously, illustrating the scope of medication therapy issues in real-world patients.
Results from this cross-sectional study of 1,346 patients, primarily from Vanderbilt University Medical Center and the Cleveland Clinic, utilizing Precera’s Precision Medicine Clinical Tool™, revealed that 63 percent of patients tested had a discrepancy between their medical record and the medications detected in their systemic circulation. This finding was particularly alarming, considering medications used to treat cardiovascular and other chronic diseases were found in patients who had no record of these co-morbidities within their disease management plan. Moreover, a disproportionate number of these unknown medications were identified as potentially harmful in combination with other therapeutics prescribed and detected in their circulation.
Study findings also revealed the following: 1) medications are frequently detected despite lack of prescription evidence in the medical record, 2) patient adherence varies by healthcare setting and drug class, 3) being adherent to one medication is a positive predictor of adherence to other medications, 4) alerts for potential drug interactions were common, with 1,245 unique alerts across 1,346 samples and 5) nearly 53 percent of major and severe alerts were associated with unknown medications.Source: PR Newswire