The Department of Orthopedics of Peking Union Medical College Hospital (PUMCH) offers a leading scoliosis center, both in China and abroad, successfully treating over 200 patient with the rare disease over the last 15 years. The Department has won the 2018 PUMCH Achievement Award.


Scoliosis is a medical condition in which a person’s spine has a sideways curve. Usually, in the form of an “S” or a “C” shaped over three dimensions, it can be mild to severe to the point where it can interfere with breathing. The cause is unknown but it is believed to be a combination of genetic and environmental factors. It can also occur due to other conditions such as muscle spasms, cerebral palsy, Marfan syndrome, and tumors such as neurofibromatosis.

Scoliosis occurs in about 3% of people.

PUMCH Department of Orthopedics

Rare diseases with accompanying scoliosis are extremely rare. The Department has been a leader in China treating such patients. Through multidisciplinary collaboration, the surgery teams in the Department have diagnosed 33 rate diseases involving 7 major systems in patients with scoliosis based on routine clinical diagnostic techniques, molecular biology, and genetic approaches. 

Rare Diseases Association with Scoliosis in China

PUMCH has diagnosed and treated the following rare diseases associated with scoliosis:

Dwarfism, congenital contractual arachnodactyly, mucolipidosis, mucopolysaccharidosis, glycogen storage disease, mitochondrial myopathy, neurodegenerative diseases, Ehlers-Danlos syndrome, Prader-Willi syndrome, Proteus syndrome, Jacro-Levin syndrome, Gilbert syndrome, Freeman-Sheldon syndrome, and spinal muscular atrophy.

PUMCH reports that in all cases they offer a multidisciplinary treatment protocol involving an improved quality of for the patients. Obviously, TrialSite News cannot substantiate these claims.


Peking Union Medical College (Beijing Xiehe Hospital) is a renowned general hospital in Beijing., China. Founded in 1921 by the Rockefeller Foundation, it is affiliated with the Peking Union Medical College (PUMC) and the Chinese Academy of Medical Sciences (CAMS). During the “Cultural Revolution,” it was named the “Anti-Imperialist Hospital.”

Recently profiled CAMS and PUMC combined to run 19 institutes, 6 hospitals, and 7 schools. CAMS has played a pivotal role in spearheading biomedical research in China—it is the country’s most comprehensive and only national biomedical research organization.

Call to Action: Interested in the rare disease research in PUMCH? TrialSite News will monitor research originating from this institution.

Source: BioSpectrum

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