New ALS Therapy in Clinical Trial Shows Promise

Jul 18, 2018 | ALS, Amyotrophic Lateral Sclerosis (ALS)

Washington University School of Medicine (WUSM) St. Louis a recently released in Science Daily, points to a promising amyotrophic lateral sclerosis (ALS) study.  Also known as “Lou Gehrig’s disease,” few survive more than a few years after diagnosis.  After a successful pre-clinical study on mice and rats, WUSM published their findings in the Journal of Clinical Investigation.  https://www.jci.org/articles/view/99081 As reported in the press release, the results “have led to a phase one/two clinical trial to investigate whether the drug could benefit people with ALS whose disease is caused by mutations in a gene called SOD1.”

Presently, the FDA has only approved two treatments for ALS and according to the WUSM release “both only modestly slow the course of the disease.”  WUSM collaborated with Ionis Pharmaceutical on the research effort.

TrialSite News refers readers to the ClinicalTrial.gov listing: https://www.clinicaltrials.gov/ct2/show/NCT02623699?id=NCT02623699&rank=1

The actual study drug BIIB067 is the focus of the phase I study sponsored with Biogen with Ionis Pharmaceuticals as a collaborator. WUSM and dozens of other investigation sites will be involved with the actual study.  For more on BIIB067 see https://alsnewstoday.com/ionis-sod1-rx-biib067/

Research/Investigative Site

Washington University School of Medicine, et al

Lead Research/Investigator

Timothy Miller, MD, PhD, the David Clayson Professor of Neurology of Washington University

Sponsor

Biogen

View article here

1 Comment

  1. Corrine Gaffin

    i was diagnosed 2011. i was diagnosed with the bulbar form of ALS and was given one year to live. My symptoms progressed quickly. Soon i was having difficulty breathing, swallowing and even walking short distances. With the help of Natural Herbal Garden natural herbs I have been able to reverse my symptoms using diet, herbs, which i feel has made the most difference. The ALS natural formula immensely helped my condition, it reversed my ALS. my slurred speech. And then the inability to eat without getting choked, breathing, and coughing. gradually disappeared. Visit NATURAL HERBAL GARDENS via their official web-site www. naturalherbalgardens. com. I’m now playing golf again. and i turned 69 today. i am glad to get my life back DON’T GIVE UP HOPE!!!

Pin It on Pinterest