NCI Trials For February 2019

Feb 10, 2019 | Cancer Clinical Trials, Oncology

The Cancer Letter recently published a list of National Cancer Institute cancer clinical trials ongoing during the month of February. TrialSite News includes the list below. Follow up with the Cancer Letter to learn more.  They are an independent newsletter and a leading source of information on development of cancer therapies, cancer research funding and health care finance, legislation and policy.

Phase I NRG-LU004

Phase I Trial of Accelerated or Conventionally Fractionated Radiotherapy Combined with MEDI4736 (Durvalumab) in PD-L1 High Locally Advanced Non-Small Cell Lung Cancer (NSCLC) (ARCHON-1)

NRG Oncology

Lin, Steven H.

(713) 563-8490

Phase I/II 10200

Combination Pinometostat and 5-Azacitidine for the Treatment of Patients with Relapsed / Refractory Acute Myeloid Leukemia, or Newly Diagnosed Patients who are Ineligible for or Unwilling to Undergo Intensive Therapy, who Harbor an 11q23 Rearrangement

JHU Sidney Kimmel Comprehensive Cancer Center LAO

Stein, Eytan M.

(212) 639-3314

Phase I/II 10212

A Phase 1b/2 Study of Pinometostat in Combination with Standard Induction Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia with MLL Rearrangement

Ohio State University Comprehensive Cancer Center LAO

Blachly, James Stewart

(614) 685-5667

Phase I/II EAA172

Phase 1/2 Study of Daratumumab, Bortezomib, Dexamethasone with or Without Venetoclax in Relapsed/Refractory Multiple Myeloma with Assessment for t(11;14) Status

ECOG-ACRIN Cancer Research Group

Thompson, Michael A.

(414) 219-4763

Phase II 10181 

A Phase 2 Study of Savolitinib in Subjects with MET Amplified Metastatic Colorectal Cancer

Duke University – Duke Cancer Institute LAO

Strickler, John Howard

(919) 681-6006

Phase II ANBL17P1                                                                 

A Pilot Induction Regimen Incorporating Chimeric 14.18 Antibody (ch14.18, dinutuximab) (NSC# 764038, IND# 4308) and Sargramostim (GM-CSF) for the Treatment of Newly Diagnosed High-Risk Neuroblastoma

Children’s Oncology Group

Federico, Sara Michele

(901) 595-7942                                     

Phase II EAQ171CD

Implementing a Virtual Tobacco Treatment in Community Oncology Practices: “Smoke Free Support Study 2.0”                                                        

ECOG-ACRIN Cancer Research Group

Park, Elyse

(617) 724-6836

Phase II S1900A

A Phase II Study of Rucaparib in Patients with Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-Small Cell Lung Cancer (LUNG-MAP Sub-Study)

SWOG

Riess, Jonathan W.

(916) 734-3772

Phase II/III A041701

A Randomized Phase II/III Study of Conventional Chemotherapy +/- Uproleselan (GMI-1271) in Older Adults with Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy           

Alliance for Clinical Trials in Oncology

Uy, Geoffrey L.

(314) 747-8439

Phase Other AEWS18B3-Q

Identifying Inherited Germline Variation Associated with Ewing Sarcoma Risk

Children’s Oncology Group

Machiela, Mitchell

(240) 760-6518

Phase Other AHOD18B2-Q

Identifying Treatment Response Predictors in Pediatric Hodgkin Lymphoma; A Validation Set for AHOD12B2                                                          

Children’s Oncology Group

Horton, Terzah M.

(832) 824-4269

Phase Other AREN18B5-Q

Genomic Analysis of Bilateral Wilms Tumor

Children’s Oncology Group

Murphy, Andrew Jackson

(901) 930-5205

Phase Other S1800NMIO       

A LUNG-MAP Version Control Protocol for Non-Matched Immunotherapy Sub-Studies

SWOG

Papadimitrakopoulou, Vassiliki A.

(713) 792-6363

Phase Other S1900BDSS

A Lung-MAP Version Control Protocol  for Biomarker-Driven Sub-Studies                      

SWOG

Papadimitrakopoulou, Vassiliki A.

(713) 792-6363

Phase Other URCC-18004CD

Understanding the Impact of Drug Shortages on Oncology Care Delivery

University of Rochester NCORP Research Base

Hill, Elaine

(585) 275-0165

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