Icahn Medical School of Medicine, Mount Sinai and Rockefeller University researchers have discovered a new use for a long-standing computational concept known as “blacklisting” as reported in EurekAlert! The blacklisting process is typically used as a form of access or spam control, blocking unwanted files and messages. However, the researchers experimented with utilizing this method as a filter to single out genetic variations in patient genomes and exomes that do not cause illness. As a result, the New York-based research group has successfully streamlined the identification of genetic drivers of disease. The method is published in the December 2018 issue of Proceedings of the National Academy of Science. See the link below for the remainder of this interesting story.