Landmark UK Study: Routine Cardiac Arrest Treatment Doubles Risk for Brain Injury!

Jul 20, 2018 | Cardiac Arrest, Epinephrine, UK

A landmark study https://www.nejm.org/doi/full/10.1056/NEJMoa1806842?query=featured_home

Report in The Guardian will potentially lead to changes in the way cardiac arrest has been treated for more than 50 years. In a UK-based study including over 8,000 people, “doctors found that adrenaline shots increased the survival rate of patients by less than 1% but nearly doubled the risk of serious brain damage.” Moreover, the study pointed out that “nearly a third of survivors who received adrenaline ended up in a vegetative state or were unable to walk and look after themselves, compared with 18% of survivors who had a placebo instead” the Guardian reports.  Study lead Gavin Perkins, professor of critical care medicine at the University of Warwick (and consultant at Heart of England NHS Foundation Trust) stated “what we’ve shown is that adrenaline can restart the heart, but it is no good for the brain.”

Research/Investigative Site

University of Warwick

Lead Research/Investigator

Gavin Perkins, professor of critical care medicine at the University of Warwick

Sponsor

National Institutes for Health Research, Health Technology Assessment Program

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