Researchers believe PSEN1 is involved in the production of the amyloid beta protein. When the gene is mutated, the protein isn’t trimmed to the best size, ends up longer and stickier and more easily forms plaques in the brain. A leading goal of Alzheimer’s treatment is to stop the plaque formation.

Lead Research/Investigators

Dr. Ken Kosick, University of California, Santa Barbara

Dr. Francisco Lopera, University of Antioquia Colombia

Source: Azheimers Association

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