Irish Health reports that Ireland currently has 423 clinical trials, and it is reported that the numbers are increasing across the board.
The Health Research Board Clinical Research Coordination Ireland (HRB CRCI) was established back in 2014 to support the clinical trials industry in Ireland. Since this institution has been formed, there has been a 43% increase in the number of Phase II and Phase III clinical trials approved in Ireland, with 66 such trials authorized in 2014 and 95 authorized in 2018.
Presently, 291 trial sites are open across the Irish network—a 117% increase of the 134 open in 2014. Moreover, it is believed that medical device company trials will grow in Ireland. In 2018, 30 medical device clinical trial studies were ongoing in Ireland.
Health Research Board Clinical Research Coordination Ireland (HRB CRCI) is an independent integrated national clinical research network, providing centralised support in the conduct of multicentre clinical trials (both commercial and academic) across Ireland. It is funded by extramural grants from the Health Research Board (HRB) and Enterprise Island (EI), supported by the its partner Universities and is hosted by Clinical Research Development Ireland (CRDI).
In 2014, the Directors of six University Clinical Research Facilities/Centres (CRF/Cs), (at University College Cork, National University of Ireland Galway, Royal College of Surgeons Ireland, University College Dublin (2 centres) and Trinity College Dublin), responded to a HRB and EI invitation to submit a proposal for the development of a network to support the conduct of multicentre clinical trials across the island of Ireland. The application was successful and led to the establishment of HRB CRCI as a collaborative partnership of the six university based CRF/Cs and their associated hospitals. HRB CRCI subsequently became operational as an organisation in May 2015.
In 2018 two new partner centres joined the group namely the Health Research Institute Clinical Research Support Unit at University Hospital Limerick and the National Children’s Research Centre at Our Lady’s Children’s Hospital, Crumlin, Dublin.
The HRB CRCI central office provides overarching support and expertise, through a range of services and activities to academia and industry. CRDI provides corporate support services to the central office. The partners provide the infrastructure, physical space and facilities, experienced research and specialist support staff and the necessary quality and oversight programs that are critical for the successful conduct of world-class patient-focused research.
HRB CRCI and the CRF/Cs facilitate research but are not in a position to independently fund research. Our now eight partner CRF/Cs have over forty years of combined research experience and include:
- HRB CRF Cork at University College Cork and Mercy University Hospital
- HRB CRF Galway at University Hospital Galway
- Royal College of Surgeons Ireland CRC at Beaumont Hospital
- University College Dublin CRCs at Mater Misericordiae University Hospital and St. Vincent’s University Hospital
- Wellcome Trust – HRB CRF at St. James’s Hospital
- HRI-CRSU:Health Research Institute Clinical Research Support Unit at University Hospital Limerick, Co Limerick.
- NCRC: National Children’s Research Centre at Our Lady’s Children’s Hospital, Crumlin, Dublin 12