Dr. Alam Gets his Randomized Controlled Trial Approved by the Bangladesh Medical Research Council

Jul 29, 2020 | Bangladesh Medical College, COVID-19, Dr. Tarek Alam, Ivermectin, News, Popular Posts

Dr. Alam Gets his Randomized Controlled Trial Approved by the Bangladesh Medical Research Council

Dr. Tarek Alam was interviewed by TrialSite News and reported “astounding results” from the administration of  Ivermectin and Doxycycline in COVID-19 patients. Dr. Alam acknowledged the need for a randomized controlled trial as he was administering the regimen under an approval from Bangladesh Medical College Protocol. The doctor based in Dhaka has now achieved his goal and will launch a randomized controlled trial August 3, 2020. The Nation’s highest medical research body, the Bangladesh Medical and Research Council (BMRC), approved the clinical trial. It’s a green light. Can Dr. Alam show the world that in fact Ivermectin does work at least better than compared to some far more expensive medications approved for COVID-19 such as Remdesivir or Favipiravir?

The May Interview

TrialSite interviewed Dr. Alam back in May, 2020. The Dhaka-based physician and professor commented that his initial work wasn’t a clinical trial but rather an ongoing hospital-specific, approved off-label use of medication for some COVID-19 patients with escalating conditions. Specifically, they combined a dosage of ivermectin 200mcg/kg once orally with Doxycycline. The doctor reported “astounding results” but that he understood a randomized controlled trial was still needed to secure sufficient “evidence.”

That Time is Now

Dr. Alam has pulled it off and will commence a formal, randomized controlled trial at his place of employ, the Bangladesh Medical College.  The trial include 150 coronavirus patients with mild symptoms at two hospitals, including Bangladesh Medical College (BMC) and Uttara Adhunik Medical College Hospital (UAMCH) in the capital starting August 3, 2020.

Approved by the university on July 28, a 20-member team will be involved led by Dr. Alam, principal investigator, along with Dr. Rubauil Morshed of the Somman Foundation who will serve as co-investigator. The two month clinical trial will be supervised by MBC and BRMC, as reported by the Dhaka Tribune. Last Wednesday, a source at the BMRC reported to the Dhaka Tribune that the BMC received the approval papers. The medical team plans on holding a press conference.

As in the interview with the TrialSite, the Dhaka Tribune reports the claim that the ivermectin and doxycycline combination regimen reduces the patient’s symptoms by 50% in just three days; the patients on average become virus-free within four days thereafter. Alam reported that when COVID-19 tests are conducted on these patients, they on average are 100% free of virus within anywhere from four to fourteen days.

For comparison Remdesivir in hospitalized cases reduces the number of illness days from 14 days down to 11 days. Of course, there are observational reports (including some from TrialSite) that Remdesivir can reduce the death rate; however, there is no formal evidence of that as of yet.

“The People’s Medicine”

If the study proves that Ivermectin in fact works, as so many physicians in various parts of the world say it does, then the BRMC is prepared to support the cheap and equitable distribution of the drug to combat COVID-19. In fact, they are considering the naming of the drug “People’s Medicine” and will charge 40 Taka or about .47 cents (US).

About the Bangladesh Medical and Research Council

Bangladesh Medical Research Council is an autonomous national research body that carries out research on medical and health sciences and plans and prioritize research in Bangladesh and is located in MohakhaliDhakaBangladesh.  The BMRC was formed back in 1972 under the orders of the president of Bangladesh at the time. It functions under the Ministry of Health and Family Welfare.

Lead Research/Investigator

Dr. Tarek Alam, MD, MBBS

Call to Action: TrialSite will monitor the study and connect with Dr. Alam in early October to check on the status. Sign up for the daily newsletter.

11 Comments

  1. ML

    Go Dr. Alam!! And truly, thank you a million times for your efforts to help humanity. Cheers!

  2. Dr. Robert Schemmer

    Kudos to Dr Alam
    The world needs an inexpensive medicine to treat Covid 19 at its earliest onset thus avoiding increased morbidity/ mortality and expensive health/ human costs

    • Ram Bahadur

      what is the status of ivermectine’s trials at max hospital in india?
      why doesn’t show the research paper any researchers yet?
      what is the matter?

      • TrialSite

        Ram,
        That study was supposed to end July 25 but according it is categorized as still recruiting.
        A few studies have released results but no peer-review journals appear to be interested thus far.
        We think it comes down to three things including 1) economics 2) ego and 3) possibly some underlying form of racism or bias.
        Best Regards,
        Publisher

  3. Gonzalo Guerra Quintero

    Agradecería Dr. Alam me informara los resultados finales. Yo soy partidario de la Ivermetina mas Nitazoxanida. Buena suerte

  4. Prateek Kulkarni

    Whatever happened to icddr trials on ivermectin. Do we have any update on it? It was supposed to be completed by Mid July… May trialsite must follow up.

    • TrialSite

      Thanks Paul,
      These physicians are organizing a major clinical trial in the U.S. southeast/sunbelt. The TrialSite will contribute capital for key staff and systems (e.g. trial master file, IXRS, etc.). Several hospitals have stepped up to participate. This must happen so that the evidence can be produced.
      Best Regards,
      Publisher

      • Prateek Kulkarni

        Hi team,

        Can we get an update on icddr’s trial on Ivermectin and doxycycline.?

        • TrialSite

          Dear Prateek,
          We are awaiting that one. We can try to check in with them next week.
          Thanks for visiting.
          Best Regards,
          Publisher

  5. pknaidu

    When hundreds of people are dying why a simple medicine which does not have significant side effects also is not given much importance which lobby is working behind it?