A Danish-led team of researchers has identified new genetic contributions to anxiety and stress-related disorders, including variants in a proposed new drug target.
The team employed the use genotypes from 32,000 Danish persons with our without anxiety and stress-related disorders, in combination with national registry data on related diagnosis in Denmark. The researchers then performed a genome-wide association study aimed at finding new risk variants, genes and pathways for the psychiatric conditions. They estimated SNP-based heritability of the elements and looking into genetic features that dovetail with those contributing to other neuropsychiatric disorders. Follow the link to a good analysis from genomeweb as well.
Sandra Meier, Dalhousie UniversitySource: Jama network