Columbia Engineering and Vanderbilt researchers are the first to demonstrate a clinically relevant model that severely damaged lungs can be regenerated to meet transplantation criteria; this breakthrough could ultimately lead to more lungs available for transplant reports Holly Evarts of Columbia Engineering.
Presently those patients that face end-stage lung disease face dire circumstances as lung transplantation procedures are severely limited by the number of available donor organs. Most (80%) donor lungs are rejected for serious but potentially reversible injuries. Clinicians have faced a critical shortage of donor organs since the 1960s.
As Ms. Evarts reports, a Columbia Engineering and Vanderbilt research team have demonstrated that severely damaged lungs can be regenerated to meet transplantation criteria. Their findings were recently published in Nature Communications.
In the publication results, the team provided an overview of the cross-circulation platform that maintained the viability and function of the donor lung and the stability of the recipient for 36 to 56 hours. Follow the link to the source for more information.