• 00:43 Story about Patient’s Life Saved by Small Trial led by Hudson Health’s Dr. Tom Pitts’ Investigation into Eculizumab for Severe COVID-19 Cases: Amy De Vos was fighting for her life. The 45-year-old, mother of three, out of a small town called Troy, Ohio (near Dayton) was in critical condition—spending 29 days in Upper Valley Medical Center with COVID-19. Now as her conditioned worsened in the hospital, her doctor, Dr. Eleina Mikhaylov, reached out to a neurologist out of New York and a Wright State alum—Dr. Tom Pitts—who had studied previous coronaviruses. He uncovered that something known as a “compliment” was attacking patient’s lungs and formulated a defense. This was in the form of a complement inhibitor called Eculizumab or Soliris. As it turns out, the FDA approved this approach on five patients—and Amy De Vos represents the first person to come out of this clinical trial using the rarely-used drug used to treat respiratory illness.
  • DAYTON24/7 NOW News Report Link: https://dayton247now.com/news/coronavirus/troy-covid-19-patient-says-clinical-trial-of-rare-drug-saved-her
  • Dr. Eleina Mikhaylov: https://www.premierhealth.com/find-a-doctor/1790984045
  • Dr. Tom Pitt’s: https://hudsonmedical.com/medical/team/thomas-pitts/
  • Dr. Tom Pitt’s FDA Study summary: https://hudsonmedical.com/articles/dr-pitts-of-hudson-medical-has-proposed-a-treatment-for-coronavirus-patients/
  • Alexion Pharmaceuticals: https://alexion.com/ 
  • 06:09 Story about# University of Baghdad Launches Ivermectin Clinical Trial for COVID-19 Patients: The valley where the Tigris and Euphrates Rivers flows down through what is now modern-day Iraq is literally a cradle of Civilization. After all, the world’s first writing occurs here in the form of cuneiform—the language of ancient Mesopotamia. Iraq’s University of Baghdad is the Arab’s world’s second largest university, and by some accounts got it’s start in 1067 AD as Abu-Haneefa. Regardless, its modern form materialized as the College of Law in 1908, and a College of Medicine launched in 1927. In 2020, the university was listed in the Times Higher Education World University Rankings. Recently the College of Medicine’s research arm launched a clinical trial to assess the safety and efficacy of adjuvant use of Ivermectin in Covid-19 patients with Pneumonia.
  • Phase I Study:
    https://en.uobaghdad.edu.iq/?p=20335
    Faiq I. Glorial:
    https://scholar.google.com/citations?user=RVGzk54AAAAJ&hl=en

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    08:52 Story About #Sinovac’s #PiCoVacc Experimental #Vaccine Shows Promise in #Monkeys Infected with #SARS-CoV-2:
    Meanwhile, A preclinical animal study in China has produced a study result that an early stage vaccine called PiCoVacc can block SARS-CoV-2. Researchers working for Sinovac Biotech Ltd. reported in a recent preprint server (not peer reviewed) study that the team administered varying doses of PiCoVacc to eight different rhesus macaque monkeys. After three weeks the researchers actually infused SARS-CoV-2 virus into the monkeys’ lungs via tubes into their tracheas and the team found that not one monkey developed the full infection. The Sinovac group summarized that the PiCoVacc product confers “complete protection in non-human primates against SARS-CoV-2 strains circulating worldwide by eliciting potent humoral responses devoid of immunopathology.”


    SARS-CoV-2 vaccine status report:
    https://www.sciencemag.org/news/2020/04/covid-19-vaccine-protects-monkeys-new-coronavirus-chinese-biotech-reports
    Jon Cohen Report:
    https://www.sciencemag.org/news/2020/04/covid-19-vaccine-protects-monkeys-new-coronavirus-chinese-biotech-reports
    Sinovac Biotech LTD Annual Report:
    http://www.sinovac.com/file/File/financialreports/SVA_2018_20F.pdf

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    13:26 Story about #Manatee #Memorial #Hospital in #Florida Ramps up Participation in COVID-19 #Convalescent #Plasma National Study:
    Manatee Memorial Hospital, a 319-bed hospital serving the citizens of Manatee, Sarasota, and surrounding counties for 65 years, is part of the Manatee Healthcare System. As part of the unprecedented challenge facing all Americans in the fight against COVID-19, this Florida provider has joined the Expanded Access Clinical Trial Program to collect and provide convalescent plasma to patients in need across the country. The national program, coordinated by the Mayo Clinic and American Red Cross, collects and administers COVID-19 convalescent plasma to eligible patients.


    Eliot W. Godofsky, MD:
    https://bachandgodofsky.com/practitioners/

 

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