Researchers from the Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago have identified distinct gene expression patterns that could lead to patient-tailored treatments in the future. The Chicago research group published the findings in Physiological Genomics. The team worked with CF patient blood samples, assessing the sequence and levels of the selected genes. Thereafter, genetic data was linked with patient clinical history available via the institution’s medical records—and compared this data with that of healthy individuals. The research evidenced that CF-specific genetic patterns may be linked to clinical outcomes in patients. Their findings are a crucial step toward CF precision medicine.
Hara Levy, MD