The Canadian Glycomics Network (GlycoNet) today awarded $3.9 million in grant funding to 11 collaborative research projects. The fund will support a wide range of multidisciplinary research teams across 17 Canadian research institutions and their industry partners to...
Genetic
Category
University of Aberdeen Participates in Huntington’s Disease Study and Patient’s Focuses on the Good
The University of Aberdeen, led by Zosia Miedzybrodzka, cares for Huntington’s disease (HD) patients, such as Sandy Patience of Scotland, as the 801 patient global study known as Generation-HD1 unfolds. Patience inherited this condition and declared the clinical...
DOE-Funded UC Berkeley’s Advanced Light Source Contributes to a Pathbreaking Experimental Cancer Drug
Amgen’s AMG 510, the first therapy to reach clinical trials that inhibits a mutant KRAS protein, has demonstrated promising safety and efficacy results based on preliminary animal studies and clinical trials ongoing. It is now entering Phase II clinical trials. It got...
Stanford Researchers Study Reveals Need for Better Understanding of Clinical Trial Risks
Stanford University researchers study concludes that clinical trials can offer patients with Huntington’s disease (HD) hope when there are no treatments available despite unknowns whether the therapy will work or is safe. The study results show that although the HD...
Kaiser Permanente Real-World Study Reveals How Patients’ Genes Affect Medication Choice
Kaiser Permanente, one of the nation’s largest health systems, conducted a real-world study to find that neurological side effects from phenytoin, an anti-seizure medication, are more common in patients with certain genetic variants. Interestingly, the same genetic...
Thermo Fisher Scientific CRISPR Libraries May Transform How Researchers Use CRISPR to open novel drug discovery
Thermo Fisher Scientific’s new gene editing tool will help researchers find therapies for cancer and other diseases. Called the Invitrogen LentiArray CRISPR Libraries, it is a ready-to-use array of knockout libraries for the human genome. The library suite offers...
University of British Columbia Study to Identify Cause of Rare Genetic Metabolic Disorder
The University of British Columbia (UBC), BC Children’s Hospital, and an international team of investigators published in the New England Journal of Medicine a rarely-seen type of DNA mutation as the potential cause of an inherited metabolic disorder. Often the result...
Mt. Sinai & Rockefeller Univ. Use Blacklist Computing to Streamline Genetic Analysis
Icahn Medical School of Medicine, Mount Sinai and Rockefeller University researchers have discovered a new use for a long-standing computational concept known as “blacklisting” as reported in EurekAlert! The blacklisting process is typically used as a form of access...
University of Exeter Research: Losing Control of Gene Activity in Alzheimer’s Disease
Read ScienceDaily about pioneering research into the mechanisms controlling gene activity in the brain could hold the key to understanding Alzheimer's disease and might help identify effective treatments in the future. Lead/Research Jonathan Mill
Genetics of Heart Rhythms Explored in Large Population Study
University of Washington (UW) reports that New knowledge about biological processes related to the heart's electrical activity has been gained through a major genome science study. The research had the largest sample size ever of a project of this type. The molecular...
Gene Therapy in Mice May Prevent Gaucher Disease
First a TrialSite News digression into Gaucher disease https://ghr.nlm.nih.gov/condition/gaucher-disease is an inherited disorder that affects many of the body’s organs and tissues. The signs and symptoms of this condition vary widely among individuals. There are...
Kuopio Center: Innovative Gene and Cell Therapy Research Site
The Kuopio Center for Gene and Cell Therapy (KCT) is a newly established research center in Kuopio Finland with a focus on the development of novel gene and cell therapy products in the advanced therapy medicinal products (ATMPs) class. According to a recent article...
Connection Between Genes and Response to Environmental Chemicals
North Carolina State University and Oregon State University researchers have identified "genetic difference in zebrafish tied to differing responses to the same environmental chemical." notes Tracey Peake of NC State News. This finding can lead to a series of...
Many Psychiatric Disorders Linked on a Generic Level and Share Specific Generic Risk Factors
The Brainstorm study, supported by Saban Research Institute of Children’s Hospital Los Angeles. As reported in EurekaAlert! The study results are being published in the June 22, 2018 issue of the Journal of Science. The research points to the fact that a number of...