An international team of researchers led by Professor Rejko Krüger, of Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg have clarified the cause for certain genetic forms of Parkinson’s disease while also identifying possible...
Cell Therapy
Category
Children’s Hospital Los Angeles Investigators Secure $4m for Regenerative Research & Cell Therapeutics
Two prominent researchers from the Saban Research Institute of Children’s Hospital Los Angeles haves secured over $4 million from the National Institute of Diabetes and Digestive and Kidney Diseases to study cellular damage and repair in both chronic kidney disease...
Seattle’s Infectious Disease Research Institute Upbeat by Initial Results of COVID-19 Study Investigating Immunotherapy
Seattle’s Infectious Disease Research Institute, a nonprofit organization, reports positive early results from a clinical trial centering on the use of immunotherapy on COVID-19 patients. According to the organization’s CEO, Dr. Corey Casper, the results are...
UNC & Baylor Study Reveals Positive Results using CAR-T Therapy on Hodgkin Lymphoma Patients
UNC Lineberger Comprehensive Cancer Center and Baylor College of Medicine in Houston have completed an early phase clinical trial showcasing the successful use of CAR-T therapy to treat Hodgkin lymphoma successfully for the first time. A powerful immuno-oncology...
Global Demand for Cell & Gene Therapy Treatments Drive Major Expansions in Production for Thermo Fisher Scientific
With rapid growth of cell and gene therapy development comes shortages and bottlenecks the require specialized manufacturing capability associated with this growth. Hence, Thermo Fischer Scientific’s recent announcement of an $180 million expansion of its viral vector...
Mount Sinai Leading a Clinical Trial Evaluating Allogeneic Stem Cell Therapy on COVID-19 ARDS Patients
Mount Sinai Health System will be conducting a study using remestemcel-L (Ryoncil), an innovative allogeneic stem cell therapy in patients with coronavirus disease 2019 (COVID-19). Mount Sinai will play a central role in a clinical trial for patients with severe acute...
Mesoblast Receives Clearance for Use of Stem Cell Therapy Product in Patients with COVID-19 ARDS
The U.S. Food and Drug Administration (FDA) approved an Investigational New Drug (IND) application from Mesoblast Limited (Nasdaq: MESO) to treat patients with acute respiratory distress syndrome (ARDS) caused by coronavirus infection (COVID-19) with intravenous...
Infectious Disease Research Institute Partners with RTP CRO FHI Clinical for COVID-19 Clinical Trial
The Infectious Disease Research Institute (IDRI), a Seattle-based not-for-profit organization, has partnered with a full-service, Research Triangle, NC-based contract research organization called FHI Clinical to support full-service research capabilities for an...
Cell Therapy Biotech Venture Raises $150m Series A Financing
Legend Biotech Corporation (Legend), a global clinical-stage biopharmaceutical company engaged in the discovery and development of novel cell therapies for oncology and other indications, raised $150 million in Series A financing. The capital infusion will go toward...
Children’s Hospital Los Angeles & Texas Centers Develop TriCAR-T Cell Therapy for Lymphoblastic Leukemia Cancer
A clinical investigator at Children’s Hospital of Los Angeles, Hisham Abdel-Azim, MD, MS, and colleagues, have completed a study where they engineered T-cells to identify and target multiple sites on acute lymphoblastic leukemia cells rather than just one. This...
U.S. FDA Reviewing Stem Cell Pioneer Celularity’s IND for Cell-Therapy-based COVID-19 Therapy
New Jersey cell therapy startup venture Celularity, founded by a cell therapy pioneer Bob Hariri, is among the first ventures to recognize the human placenta as an untapped resource for innovation—and, in fact, the foundation of their science is built on innovations...
German Government Injects €2.45m to ‘Get to Root of Problem’ of Leukemia: Preliminary Stem Cell-based Research
The German Federal Ministry of Education and Research (BMBF), has transferred €2.45m to a research collaborative known as LeukoSyStem to “get to the root of the problem” of leukemia. With an emphasis on stem cell research and “the starting point of leukemia,” the...
Elite Research Centers Ink Deal with Lonza to Evaluate (Pilot) Cell Therapy Manufacturing for Next Generation Treatments
In a notable partnership, Switzerland-based Lonza inked a partnership with leading research institutes and academic medical centers including Stanford University School of Medicine, Fred Hutchinson Cancer Research Center and Parker Institute for Cancer Immunotherapy...
Nationwide Children’s Hospital Submits Proposal to HHS to use Genetically Engineered NK Cells Targeting COVID-19
Nationwide Children’s Hospital (NCH), a global hub for advanced gene therapy discovery, has submitted a proposal to the Biomedical Advanced Research and Development Authority of the U.S. Department of Health and Human Services (HHS) to pursue possible treatments...
CSL Behring & University City Science Center Accelerate Research for New Biotherapies with Grant Awards
University of Pittsburgh and University of Delaware researchers received funding for research covering innovative therapies targeting pulmonary fibrosis (FB) to Gene delivery to or editing Hematopoietic (blood) Stem and Progenitor Cells (HSPCs). Two clinical...
Duke Participates in the BEAT-MS Clinical Trial Comparing Stem Cell Transplantation to Immunotherapy
Duke University, through the Immune Tolerance Network, is offering a multicenter, Phase III interventional clinical trial examining the efficacy of autologous hematopoietic stem cell transplantation, an emerging therapy for patients with active, treatment-resistant,...
UT Southwestern Inks Deal to Collaborate to Ultimately Master ‘Exotransplantation’ for Regenerative Medicine Research
University of Texas Southwestern (UTSW) inked a collaborative research deal with Recombinetics (RCI) to identify key factors that improve the efficiency of generating interspecies chimera between pigs and humans. The parties entered into this agreement to contribute...
Indapta Therapeutics & Lonza to Develop G-NK Cell Therapy
A new partnership seeks to advance an experimental new off-the-shelf cell therapy designed to treat multiple types of cancers, such as multiple myeloma. Announced by Lonza and Indapta Therapeutics, this effort seeks to progress G-NK cell therapy, originating from the...
Cardiff University Researchers Make Universal Cancer Treatment Involving Immunotherapy
Researchers at Cardiff University’s School of Medicine have discovered a new method for killing an array of cancers such as prostate, breast, lung, and others. The group of investigators, based in Wales, has developed a process that utilizes T-cell receptors within...
Breakthrough Sheba Medical Center-Originated Cell Therapy Leads to Rejuvenation of Kidney
What is there was a way to rejuvenate the kidneys so that there was no need for dialysis? That is exactly what researchers from Sheba Medical Center have been working on, with recent insights published in the journal Cell Reports. The researchers demonstrated that it...